SFB 1032: Nanoagents for Spatiotemporal Control of Molecular and Cellular Reactions

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DNA scaffolds, rafts and switchable supported lipid membranes studied by x-rays

Project A7 studies the assembly and time controlled switching of nanoagents at interfaces. We use small angle x-ray scattering to characterize conformational transitions of DNA origami and DNA crystallization of larger assemblies on surfaces. Using time resolved x-ray experiments we study the response of lipid assemblies to lipid-photoswitching. We build cushioned membrane surfaces for localized release of ions by means of photo-induced membrane permeabilization. Ion loading and release are quantified using conductive organic films and fluorescence assays.