SFB 1032: Nanoagents for Spatiotemporal Control of Molecular and Cellular Reactions

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Formation of Pattern and Shape in Confined Cellular Systems

The formation of patterns and morphologies, and the emergence of collective behavior in biological systems are achieved by an intricate interplay between spatial and temporal heterogeneities, cross-talk between discrete units, and complex biochemical networks. Our goal is to develop computa-tional and analytical models to gain deeper insights into collective migration patterns in multi-cellular systems, as well as the pattern forming capabilities of biomolecular reaction-diffusion systems in complex geometries.The theoretical analysis will be based on cellular automata, numerical investi-gation of partial differential equations, and methods adapted from nonlinear dynamics.