SFB 1032: Nanoagents for Spatiotemporal Control of Molecular and Cellular Reactions

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Joint CeNS Colloquium with SFB1032

Prof. Marino Arroyo, Universitat Politècnica de Catalunya-Barcelona Tech

02.12.2022 at 15:30 

Title: Cytoskeletal dynamics and the active self organization within cells and in cell monolayers

Location: Faculty of Physics, Kleiner Physikhörsaal N020 and online via Zoom

Host: Prof. Erwin Frey, Prof. Steffen Rulands, Prof. Claudia Veigel

Summary: The actin cytoskeleton is an adaptive and polymorphic structural network within cells, which performs a number of cellular mechanical functions including their ability to exert forces, to reshape or to move. Prominent architectures include isotropic states, polar spikes or sheets, and dense nematic bundles. However, the physical mechanisms leading to these mesoscale architectures are not well understood. In the first part of the talk, I will discuss a theory and computations to understand the active self-organization of patterns of dense nematic bundles and how they couple to cell shape. The dynamics of the actin cytoskeleton also operate at the supra-cellular level, where they control the rheology of cellular tissues. In the second part of the talk, I will discuss an integrated theory-experiment approach to understand tissue mechanics and dynamics, and how this understanding allows us to direct morphogenesis in vitro.


see also CeNS-colloquiums-website

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