SFB 1032: Nanoagents for Spatiotemporal Control of Molecular and Cellular Reactions
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Publications Area B

B01

"Membrane-Mediated Self-Organization of Rod-Like DNA Origami on Supported Lipid Bilayers"
A. Khmelinskaia, H. G. Franquelim, R. Yaadav, E. P. Petrov, P. Schwille (A09)
Advanced Materials Interfaces, 2021, 8 (24), DOI: 10.1002/admi.202101094

"Live-cell Imaging of Single-Cell Arrays (LISCA) - a Versatile Technique to Quantify Cellular Kinetics"
A. Reiser, D. Woschee, S. M. Kempe, J. O. Rädler (A07&B01)
Jove-Journal of Visualized Experiments, 2021, (169), DOI: 10.3791/62025

"Learning the dynamics of cell-cell interactions in confined cell migration"
D. B. Bruckner, N. Arlt, A. Fink, P. Ronceray, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (7), DOI: 10.1073/pnas.2016602118

"On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes"
C. Schreiber, B. Amiri, J. C. J. Heyn, J. O. Rädler (A07&B01), M. Falcke
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (4), DOI: 10.1073/pnas.2009959118

"Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform"
D. M. Loy, R. Krzyszton, U. Lachelt, J. O. Rädler (A07&B01), E. Wagner (B04)
Processes, 2021, 9 (1), DOI: 10.3390/pr9010129

"Quasi-periodic migration of single cells on short microlanes"
F. Zhou, S. A. Schaffer, C. Schreiber, F. J. Segerer, A. Goychuk, E. Frey (B02), J. O. Rädler (A07&B01)
PLoS One, 2020, 15 (4), DOI: 10.1371/journal.pone.0230679

"A Method for High-Throughput Measurements of Viscosity in Sub-micrometer-Sized Membrane Systems"
G. Chwastek, E. P. Petrov, J. P. Saenz
Chembiochem, 2020, 21 (6), pp 836-844, DOI: 10.1002/cbic.201900510

"Area and Geometry Dependence of Cell Migration in Asymmetric Two-State Micropatterns"
A. Fink, D. B. Bruckner, C. Schreiber, P. J. F. Rottgermann, C. P. Broedersz (B12), J. O. Rädler (A07&B01)
Biophysical Journal, 2020, 118 (3), pp 552-564, DOI: 10.1016/j.bpj.2019.11.3389

"Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A"
B. Ljepoja, C. Schreiber, F. A. Gegenfurtner, J. Garcia-Roman, B. Kohler, S. Zahler (B08), J. O. Rädler (A07&B01), E. Wagner (B04), A. Roidl
PLoS One, 2019, 14 (11), DOI: 10.1371/journal.pone.0224314

"A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure-activity relationship"
D. M. Loy, P. M. Klein, R. Krzysztoń, U. Lächelt, J. O. Rädler (A07&B01), E. Wagner (B04)
PeerJ Materials Science, 2019, 1, p pp e1, DOI: 10.7717/peerj-matsci.1

"Single-cell kinetics of siRNA-mediated mRNA degradation"
R. Krzyszton, D. Woschee, A. Reiser, G. Schwake, H. H. Strey, J. O. Rädler (A07&B01)
Nanomedicine-Nanotechnology Biology and Medicine, 2019, 21, DOI: 10.1016/j.nano.2019.102077

"Correlation of mRNA delivery timing and protein expression in lipid-based transfection"
A. Reiser, D. Woschee, N. Mehrotra, R. Krzyszton, H. H. Strey, J. O. Rädler (A07&B01)
Integrative Biology, 2019, 11 (9), pp 362-371, DOI: 10.1093/intbio/zyz030

"Stochastic nonlinear dynamics of confined cell migration in two-state systems"
D. B. Bruckner, A. Fink, C. Schreiber, P. J. F. Rottgermann, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Nature Physics, 2019, 15 (6), pp 595-+, DOI: 10.1038/s41567-019-0445-4

"A single-cell micro-trench platform for automatic monitoring of cell division and apoptosis after chemotherapeutic drug administration"
E. I. Chatzopoulou, P. Raharja-Liu, A. Murschhauser, F. Sekhavati, F. Buggenthin, A. M. Vollmar, C. Marr, J. O. Rädler (A07&B01)
Scientific Reports, 2018, 8, DOI: 10.1038/s41598-018-36508-8

"Control of Membrane Binding and Diffusion of Cholesteryl-Modified DNA Origami Nanostructures by DNA Spacers"
A. Khmelinskaia, J. Mucksch, E. P. Petrov, H. G. Franquelim, P. Schwille (A09)
Langmuir, 2018, 34 (49), pp 14921-14931, DOI: 10.1021/acs.langmuir.8b01850

"Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing"
F. A. Gegenfurtner, B. Jahn, H. Wagner, C. Ziegenhain, W. Enard, L. Geistlinger, J. O. Rädler (A07&B01), A. M. Vollmar, S. Zahler (B08)
Journal of Cell Science, 2018, 131 (10), DOI: 10.1242/jcs.212886

"Guiding 3D cell migration in deformed synthetic hydrogel microstructures"
M. Dietrich, H. Le Roy, D. B. Bruckner, H. Engelke (B11), R. Zantl, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Soft Matter, 2018, 14 (15), pp 2816-2826, DOI: 10.1039/c8sm00018b

"Nanomaterial interactions with biomembranes: Bridging the gap between soft matter models and biological context"
M. Werner, T. Auth, P. A. Beales, J. B. Fleury, F. Hook, H. Kress, R. C. Van Lehn, M. Muller, E. P. Petrov, L. Sarkisov, J. U. Sommer, V. A. Baulin
Biointerphases, 2018, 13 (2), DOI: 10.1116/1.5022145

"Single Cell Microarrays Fabricated by Microscale Plasma-Initiated Protein Patterning (mu PIPP)"
A. Reiser, M. L. Zorn, A. Murschhauser, J. O. Rädler (A07&B01)
book chapter to appear in Cell-Based Microarrays: Methods and Protocols, 2018, 1771, pp 41-54, DOI: 10.1007/978-1-4939-7792-5_4

"Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia"
D. J. Lee, E. Kessel, T. Lehto, X. Y. Liu, N. Yoshinaga, K. Padari, Y. C. Chen, S. Kempter, S. Uchida, J. O. Rädler (A07&B01), M. Pooga, M. T. Sheu, K. Kataoka, E. Wagner (B04)
Bioconjugate Chemistry, 2017, 28 (9), pp 2393-2409, DOI: 10.1021/acs.bioconjchem.7b00383

"Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles"
R. Krzyszton, B. Salem, D. J. Lee, G. Schwake, E. Wagner (B04), J. O. Rädler (A07&B01)
Nanoscale, 2017, 9 (22), pp 7442-7453, DOI: 10.1039/c7nr01593c

"Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks"
R. Roder, T. Preiss, P. Hirschle, B. Steinborn, A. Zimpel, M. Hohn, J. O. Rädler (A07&B01), T. Bein (B05), E. Wagner (B04), S. Wuttke, U. Lachelt
Journal of the American Chemical Society, 2017, 139 (6), pp 2359-2368, DOI: 10.1021/jacs.6b11934

"Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes"
D. J. Lee, D. S. He, E. Kessel, K. Padari, S. Kempter, U. Lachelt, J. O. Rädler (A07&B01), M. Pooga, E. Wagner (B04)
Journal of Controlled Release, 2016, 244, pp 280-291, DOI: 10.1016/j.jconrel.2016.06.011

"Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments"
S. L. Schuster, F. J. Segerer, F. A. Gegenfurtner, K. Kick, C. Schreiber, M. Albert, A. M. Vollmar, J. O. Rädler (A07&B01), S. Zahler (B08)
Biomaterials, 2016, 102, pp 137-147, DOI: 10.1016/j.biomaterials.2016.06.021

"Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell"
W. Zhang, K. Muller, E. Kessel, S. Reinhard, D. S. He, P. M. Klein, M. Hohn, W. Rodl, S. Kempter, E. Wagner (B04)
Advanced Healthcare Materials, 2016, 5 (12), pp 1493-1504, DOI: 10.1002/adhm.201600057

"Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration"
C. Schreiber, F. J. Segerer, E. Wagner (B04), A. Roidl, J. O. Rädler (A07&B01)
Scientific Reports, 2016, 6, DOI: 10.1038/srep26858

"Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers"
A. Zimpel, T. Preiss, R. Roder, H. Engelke (B11), M. Ingrisch, M. Peller, J. O. Rädler (A07&B01), E. Wagner (B04), T. Bein (B05), U. Lachelt, S. Wuttke
Chemistry of Materials, 2016, 28 (10), pp 3318-3326, DOI: 10.1021/acs.chemmater.6b00180

"Versatile method to generate multiple types of micropatterns"
F. J. Segerer, P. J. F. Rottgermann, S. Schuster, A. P. Alberola, S. Zahler (B08), J. O. Rädler (A07&B01)
Biointerphases, 2016, 11 (1), DOI: 10.1116/1.4940703

"Exploration of MOF nanoparticle sizes using various physical characterization methods - is what you measure what you get?"
P. Hirschle, T. Preiss, F. Auras, A. Pick, J. Volkner, D. Valdeperez, G. Witte, W. J. Parak, J. O. Rädler (A07&B01), S. Wuttke
Crystengcomm, 2016, 18 (23), pp 4359-4368, DOI: 10.1039/c6ce00198j

"Chip-based platform for dynamic analysis of NK cell cytolysis mediated by a triplebody"
E. I. Chatzopoulou, C. C. Roskopf, F. Sekhavati, T. A. Braciak, N. C. Fenn, K. P. Hopfner, F. S. Oduncu, G. H. Fey, J. O. Rädler (A07&B01)
Analyst, 2016, 141 (7), pp 2284-2295, DOI: 10.1039/c5an02585k

"Phenomenological approaches to collective behavior in epithelial cell migration"
M. L. Zorn, A. K. Marel, F. J. Segerer, J. O. Rädler (A07&B01)
Biochimica Et Biophysica Acta-Molecular Cell Research, 2015, 1853 (11), pp 3143-3152, DOI: 10.1016/j.bbamcr.2015.05.021

"Emergence and Persistence of Collective Cell Migration on Small Circular Micropatterns"
F. J. Segerer, F. Thuroff, A. P. Alberola, E. Frey (B02), J. O. Rädler (A07&B01)
Physical Review Letters, 2015, 114 (22), DOI: 10.1103/PhysRevLett.114.228102

"Stability analysis of chemically modified mRNA using micropattern-based single-cell arrays"
M. Ferizi, C. Leonhardt, C. Meggle, M. K. Aneja, C. Rudolph, C. Plank, J. O. Rädler (A07&B01)
Lab on a Chip, 2015, 15 (17), pp 3561-3571, DOI: 10.1039/c5lc00749f

"MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells"
S. Wuttke, S. Braig, T. Preiss, A. Zimpel, J. Sicklinger, C. Bellomo, J. O. Rädler (A07&B01), A. M. Vollmar, T. Bein (B05)
Chemical Communications, 2015, 51 (87), pp 15752-15755, DOI: 10.1039/c5cc06767g

"Marker-free detection of progenitor cell differentiation by analysis of Brownian motion in micro-wells"
F. Sekhavati, M. Endele, S. Rappl, A. K. Marel, T. Schroeder, J. O. Rädler (A07&B01)
Integrative Biology, 2015, 7 (2), pp 178-183, DOI: 10.1039/c4ib00158c

"Cell Motility on Polyethylene Glycol Block Copolymers Correlates to Fibronectin Surface Adsorption"
P. J. F. Rottgermann, S. Hertrich, I. Berts, M. Albert, F. J. Segerer, J. F. Moulin, B. Nickel (A07), J. O. Rädler (A07&B01)
Macromolecular Bioscience, 2014, 14 (12), pp 1755-1763, DOI: 10.1002/mabi.201400246

"Alignment of cell division axes in directed epithelial cell migration"
A. K. Marel, N. Podewitz, M. Zorn, J. O. Rädler (A07&B01), J. Elgeti
New Journal of Physics, 2014, 16, DOI: 10.1088/1367-2630/16/11/115005

"The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility"
M. H. Menhofer, R. Kubisch, L. Schreiner, M. Zorn, F. Foerster, R. Mueller, J. O. Rädler (A07&B01), E. Wagner (B04), A. M. Vollmar, S. Zahler (B08)
PLoS One, 2014, 9 (11), DOI: 10.1371/journal.pone.0112542

"Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes"
T. S. Ligon, C. Leonhardt, J. O. Rädler (A07&B01)
PLoS One, 2014, 9 (9), DOI: 10.1371/journal.pone.0107148

"Flow and Diffusion in Channel-Guided Cell Migration"
A. K. Marel, M. Zorn, C. Klingner, R. Wedlich-Soldner, E. Frey (B02), J. O. Rädler (A07&B01)
Biophysical Journal, 2014, 107 (5), pp 1054-1064, DOI: 10.1016/j.bpj.2014.07.017

"Single-cell mRNA transfection studies: Delivery, kinetics and statistics by numbers"
C. Leonhardt, G. Schwake, T. R. Stogbauer, S. Rappl, J. T. Kuhr, T. S. Ligon, J. O. Rädler (A07&B01)
Nanomedicine-Nanotechnology Biology and Medicine, 2014, 10 (4), pp 679-688, DOI: 10.1016/j.nano.2013.11.008

"Cellular self-organization on micro-structured surfaces"
P. J. F. Rottgermann, A. P. Alberola, J. O. Rädler (A07&B01)
Soft Matter, 2014, 10 (14), pp 2397-2404, DOI: 10.1039/c3sm52419a

"Arraying Cell Cultures Using PEG-DMA Micromolding in Standard Culture Dishes"
A. K. Marel, S. Rappl, A. P. Alberola, J. O. Rädler (A07&B01)
Macromolecular Bioscience, 2013, 13 (5), pp 595-602, DOI: 10.1002/mabi.201200400

"Nucleic acid nanostructures for biomedical applications"
D. Smith, V. Schuller, C. Engst, J. Rädler (A07&B01), T. Liedl (A06)
Nanomedicine, 2013, 8 (1), pp 105-121, DOI: 10.2217/NNM.12.184

B02

"Control of protein-based pattern formation via guiding cues"
T. Burkart, M. C. Wigbers, L. Wurthner, E. Frey (B02)
Nature Reviews Physics, 2022, DOI: 10.1038/s42254-022-00461-3

"Surface-tension-induced budding drives alveologenesis in human mammary gland organoids"
P. A. Fernandez, B. Buchmann, A. Goychuk, L. K. Engelbrecht, M. K. Raich, C. H. Scheel, E. Frey (B02), A. R. Bausch (A10)
Nature Physics, 2021, 17 (10), pp 1130-+, DOI: 10.1038/s41567-021-01336-7

"A diffusiophoretic mechanism for ATP-driven transport without motor proteins"
B. Ramm, A. Goychuk, A. Khmelinskaia, P. Blumhardt, H. Eto, K. A. Ganzinger, E. Frey (B02), P. Schwille (A09)
Nature Physics, 2021, 17 (7), pp 850-+, DOI: 10.1038/s41567-021-01213-3

"Bulk-surface coupling identifies the mechanistic connection between Min-protein patterns in vivo and in vitro"
F. Brauns, G. Pawlik, J. Halatek, J. Kerssemakers, E. Frey (B02), C. Dekker
Nature Communications, 2021, 12 (1), DOI: 10.1038/s41467-021-23412-5

"A hierarchy of protein patterns robustly decodes cell shape information"
M. C. Wigbers, T. H. Tan, F. Brauns, J. H. Liu, S. Z. Swartz, E. Frey (B02), N. Fakhri
Nature Physics, 2021, 17 (5), pp 578-+, DOI: 10.1038/s41567-021-01164-9

"Wavelength Selection by Interrupted Coarsening in Reaction-Diffusion Systems"
F. Brauns, H. Weyer, J. Halatek, J. Yoon, E. Frey (B02)
Physical Review Letters, 2021, 126 (10), DOI: 10.1103/PhysRevLett.126.104101

"Diffusive coupling of two well-mixed compartments elucidates elementary principles of protein-based pattern formation"
F. Brauns, J. Halatek, E. Frey (B02)
Physical Review Research, 2021, 3 (1), DOI: 10.1103/PhysRevResearch.3.013258

"Cell-Based Strain Remodeling of a Nonfibrous Matrix as an Organizing Principle for Vasculogenesis"
D. Rudiger, K. Kick, A. Goychuk, A. M. Vollmar, E. Frey (B02), S. Zahler (B08)
Cell Reports, 2020, 32 (6), DOI: 10.1016/j.celrep.2020.108015

"Flow Induced Symmetry Breaking in a Conceptual Polarity Model"
M. C. Wigbers, F. Brauns, C. Y. Leung, E. Frey (B02)
Cells, 2020, 9 (6), DOI: 10.3390/cells9061524

"Quasi-periodic migration of single cells on short microlanes"
F. Zhou, S. A. Schaffer, C. Schreiber, F. J. Segerer, A. Goychuk, E. Frey (B02), J. O. Rädler (A07&B01)
PLoS One, 2020, 15 (4), DOI: 10.1371/journal.pone.0230679

"Pattern localization to a domain edge"
M. C. Wigbers, F. Brauns, T. Hermann, E. Frey (B02)
Physical Review E, 2020, 101 (2), DOI: 10.1103/PhysRevE.101.022414

"Geometric cues stabilise long-axis polarisation of PAR protein patterns in C. elegans"
R. Gessele, J. Halatek, L. Wurthner, E. Frey (B02)
Nature Communications, 2020, 11 (1), DOI: 10.1038/s41467-020-14317-w

"Bridging the gap between single-cell migration and collective dynamics"
F. Thuroff, A. Goychuk, M. Reiter, E. Frey (B02)
Elife, 2019, 8, DOI: 10.7554/eLife.46842

"Design of biochemical pattern forming systems from minimal motifs"
P. Glock, F. Brauns, J. Halatek, E. Frey (B02), P. Schwille (A09)
Elife, 2019, 8, DOI: 10.7554/eLife.48646

"Protein Recruitment through Indirect Mechanochemical Interactions"
A. Goychuk, E. Frey (B02)
Physical Review Letters, 2019, 123 (17), DOI: 10.1103/PhysRevLett.123.178101

"Active matter invasion"
F. Kempf, R. Mueller, E. Frey (B02), J. M. Yeomans, A. Doostmohammadi
Soft Matter, 2019, 15 (38), pp 7538-7546, DOI: 10.1039/c9sm01210a

"Self-organization principles of intracellular pattern formation"
J. Halatek, F. Brauns, E. Frey (B02)
Philosophical Transactions of the Royal Society B-Biological Sciences, 2018, 373 (1747), DOI: 10.1098/rstb.2017.0107

"Rethinking pattern formation in reaction-diffusion systems"
J. Halatek, E. Frey (B02)
Nature Physics, 2018, 14 (5), pp 507-+, DOI: 10.1038/s41567-017-0040-5

"MinE conformational switching confers robustness on self-organized Min protein patterns"
J. Denk, S. Kretschmer, J. Halatek, C. Hartl, P. Schwille (A09), E. Frey (B02)
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (18), pp 4553-4558, DOI: 10.1073/pnas.1719801115

"Protein Pattern Formation"
E. Frey, J. Halatek, S. Kretschmer, P. Schwille (A09)
book chapter to appear in Physics of Biological Membranes, 2018, edited by P. Bassereau, P. Sens, pp 229-260, DOI: 10.1007/978-3-030-00630-3_10

"Morphology and Motility of Cells on Soft Substrates"
A. Goychuk, D. B. Brückner, A. W. Holle, J. P. Spatz, C. P. Broedersz (B12), E. Frey (B02)
arXiv preprint, 2018, DOI: 10.48550/ARXIV.1808.00314

"Multistability and dynamic transitions of intracellular Min protein patterns"
F. B. Wu, J. Halatek, M. Reiter, E. Kingma, E. Frey (B02), C. Dekker
Molecular Systems Biology, 2016, 12 (6), DOI: 10.15252/msb.20156724

"Magnetic Propulsion of Microswimmers with DNA-Based Flagellar Bundles"
A. M. Maier, C. Weig, P. Oswald, E. Frey (B02), P. Fischer, T. Liedl (A06)
Nano Letters, 2016, 16 (2), pp 906-910, DOI: 10.1021/acs.nanolett.5b03716

"Geometry-induced protein pattern formation"
D. Thalmeier, J. Halatek, E. Frey (B02)
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (3), pp 548-553, DOI: 10.1073/pnas.1515191113

"Emergence and Persistence of Collective Cell Migration on Small Circular Micropatterns"
F. J. Segerer, F. Thuroff, A. P. Alberola, E. Frey (B02), J. O. Rädler (A07&B01)
Physical Review Letters, 2015, 114 (22), DOI: 10.1103/PhysRevLett.114.228102

"Flow and Diffusion in Channel-Guided Cell Migration"
A. K. Marel, M. Zorn, C. Klingner, R. Wedlich-Soldner, E. Frey (B02), J. O. Rädler (A07&B01)
Biophysical Journal, 2014, 107 (5), pp 1054-1064, DOI: 10.1016/j.bpj.2014.07.017

"GDI-Mediated Cell Polarization in Yeast Provides Precise Spatial and Temporal Control of Cdc42 Signaling"
B. Klunder, T. Freisinger, R. Wedlich-Soldner, E. Frey (B02)
Plos Computational Biology, 2013, 9 (12), DOI: 10.1371/journal.pcbi.1003396

"Stability of Localized Wave Fronts in Bistable Systems"
S. Rulands, B. Klunder, E. Frey (B02)
Physical Review Letters, 2013, 110 (3), DOI: 10.1103/PhysRevLett.110.038102

B03

"Dynamics of HIV-1 Gag Processing as Revealed by Fluorescence Lifetime Imaging Microscopy and Single Virus Tracking"
C. Qian, A. Flemming, B. Müller, D. C. Lamb (B03)
Viruses-Basel, 2022, 14 (2), DOI: 10.3390/v14020340, Publication Date (Web): 20220208

"Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides c(th)GAMP"
S. Veth, A. Fuchs, D. Ozdemir, C. Dialer, D. J. Drexler, F. Knechtel, G. Witte, K. P. Hopfner, T. Carell (A05), E. Ploetz
Chembiochem, 2022, DOI: 10.1002/cbic.202200005

"Single Crystals Heterogeneity Impacts the Intrinsic and Extrinsic Properties of Metal-Organic Frameworks"
A. Fuchs, P. Mannhardt, P. Hirschle, H. Z. Wang, I. Zaytseva, Z. Ji, O. Yaghi, S. Wuttke, E. Ploetz
Advanced Materials, 2022, 34 (3), DOI: 10.1002/adma.202104530

"Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds"
C. A. Karg, S. J. Wang, N. Al Danaf, R. P. Pemberton, D. Bernard, M. Kretschmer, S. Schneider (A12), T. Zisis, A. M. Vollmar, D. C. Lamb (B03), S. Zahler (B08), S. Moser
Angewandte Chemie-International Edition, 2021, 60 (41), pp 22578-22584, DOI: 10.1002/anie.202107813

"Structural basis of rotavirus RNA chaperone displacement and RNA annealing"
J. P. K. Bravo, K. Bartnik, L. Venditti, J. Acker, E. H. Gail, A. Colyer, C. Davidovich, D. C. Lamb (B03), R. Tuma, A. N. Calabrese, A. Borodavka
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (41), DOI: 10.1073/pnas.2100198118

"Methods for elucidating the structural-property relationship in luminescent materials"
C. Kirst, N. A. Danaf, F. Knechtel, T. Arczynski, P. Mayer, D. C. Lamb (B03), K. L. Karaghiosoff
Journal of Materials Chemistry C, 2021, 9 (38), pp 13366-13375, DOI: 10.1039/d1tc02634h

"Linker Exchange via Migration along the Backbone in Metal-Organic Frameworks"
N. Al Danaf, W. Schrimpf, P. Hirschle, D. C. Lamb (B03), Z. Ji, S. Wuttke
Journal of the American Chemical Society, 2021, 143 (28), pp 10541-10546, DOI: 10.1021/jacs.1c04804

"Sponges as bioindicators for microparticulate pollutants?"
E. B. Girard, A. Fuchs, M. Kaliwoda, M. Lasut, E. Ploetz, W. W. Schmahl, G. Worheide
Environmental Pollution, 2021, 268, DOI: 10.1016/j.envpol.2020.115851

"Metal-Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH"
E. Ploetz, A. Zimpel, V. Cauda, D. Bauer, D. C. Lamb (B03), C. Haisch, S. Zahler (B08), A. M. Vollmar, S. Wuttke, H. Engelke (B11)
Advanced Materials, 2020, 32 (19), p pp 8, DOI: 10.1002/adma.201907267

"Trajectory data of antero- and retrograde movement of mitochondria in living zebrafish larvae"
F. Mieskes, F. Wehnekamp, G. Plucinska, R. Thong, T. Misgeld, D. C. Lamb (B03)
Data in Brief, 2020, 29, DOI: 10.1016/j.dib.2020.105280

"Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides"
J. Kuhn, Y. Lin, A. K. Levacic, N. Al Danaf, L. Peng, M. Hohn, D. C. Lamb (B03), E. Wagner (B04), U. Lachelt
Bioconjugate Chemistry, 2020, 31 (3), pp 729-742, DOI: 10.1021/acs.bioconjchem.9b00853

"A DNA Origami Platform for Single-Pair Forster Resonance Energy Transfer Investigation of DNA-DNA Interactions and Ligation"
K. Bartnik, A. Barth, M. Pilo-Pais, A. H. Crevenna, T. Liedl (A06), D. C. Lamb (B03)
Journal of the American Chemical Society, 2020, 142 (2), pp 815-825, DOI: 10.1021/jacs.9b09093

"Supramolecular Assembly of Aminoethylene-Lipopeptide PMO Conjugates into RNA Splice-Switching Nanomicelles"
J. Kuhn, P. M. Klein, N. Al Danaf, J. Z. Nordin, S. Reinhard, D. M. Loy, M. Hohn, S. El Andaloussi, D. C. Lamb (B03), E. Wagner (B04), Y. Aoki, T. Lehto, U. Lachelt
Advanced Functional Materials, 2019, 29 (48), DOI: 10.1002/adfm.201906432

"Active matter invasion"
F. Kempf, R. Mueller, E. Frey (B02), J. M. Yeomans, A. Doostmohammadi
Soft Matter, 2019, 15 (38), pp 7538-7546, DOI: 10.1039/c9sm01210a

"Actin stabilizing compounds show specific biological effects due to their binding mode"
S. J. Wang, A. H. Crevenna, I. Ugur, A. Marion, I. Antes, U. Kazmaier, M. Hoyer, D. C. Lamb (B03), F. Gegenfurtner, Z. Kliesmetes, C. Ziegenhain, W. Enard, A. Vollmar, S. Zahler (B08)
Scientific Reports, 2019, 9, DOI: 10.1038/s41598-019-46282-w

"Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo"
F. Wehnekamp, G. Plucinska, R. Thong, T. Misgeld, D. C. Lamb (B03)
Elife, 2019, 8, DOI: 10.7554/eLife.46059

"Tuning porosity in macroscopic monolithic metal-organic frameworks for exceptional natural gas storage"
B. M. Connolly, M. Aragones-Anglada, J. Gandara-Loe, N. A. Danaf, D. C. Lamb (B03), J. P. Mehta, D. Vulpe, S. Wuttke, J. Silvestre-Albero, P. Z. Moghadam, A. E. H. Wheatley, D. Fairen-Jimenez
Nature Communications, 2019, 10, DOI: 10.1038/s41467-019-10185-1

"Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface"
A. Zimpel, N. Al Danaf, B. Steinborn, J. Kuhn, M. Hohn, T. Bauer, P. Hirschle, W. Schrimpf, H. Engelke (B11), E. Wagner (B04), M. Barz, D. C. Lamb (B03), U. Lachelt, S. Wuttke
ACS Nano, 2019, 13 (4), pp 3884-3895, DOI: 10.1021/acsnano.8b06287

"Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone"
F. A. Gegenfurtner, T. Zisis, N. Al Danaf, W. Schrimpf, Z. Kliesmete, C. Ziegenhain, W. Enard, U. Kazmaier, D. C. Lamb (B03), A. M. Vollmar, S. Zahler (B08)
Cellular and Molecular Life Sciences, 2018, 75 (24), pp 4539-4555, DOI: 10.1007/s00018-018-2919-4

"Stability of local secondary structure determines selectivity of viral RNA chaperones"
J. P. K. Bravo, A. Borodavka, A. Barth, A. N. Calabrese, P. Mojzes, J. J. B. Cockburn, D. C. Lamb (B03), R. Tuma
Nucleic Acids Research, 2018, 46 (15), pp 7924-7937, DOI: 10.1093/nar/gky394

"PAM: A Framework for Integrated Analysis of Imaging, Single-Molecule, and Ensemble Fluorescence Data"
W. Schrimpf, A. Barth, J. Hendrix, D. C. Lamb (B03)
Biophysical Journal, 2018, 114 (7), pp 1518-1528, DOI: 10.1016/j.bpj.2018.02.035

"Chemical diversity in a metal-organic framework revealed by fluorescence lifetime imaging"
W. Schrimpf, J. C. Jiang, Z. Ji, P. Hirschle, D. C. Lamb (B03), O. M. Yaghi, S. Wuttke
Nature Communications, 2018, 9, DOI: 10.1038/s41467-018-04050-w

"A self-assembled nanoscale robotic arm controlled by electric fields"
E. Kopperger, J. List, S. Madhira, F. Rothfischer, D. C. Lamb (B03), F. C. Simmel (A02)
Science, 2018, 359 (6373), pp 296-300, DOI: 10.1126/science.aao4284

"Directional Photonic Wire Mediated by Homo-Forster Resonance Energy Transfer on a DNA Origami Platform"
F. Nicoli, A. Barth, W. Bae, F. Neukirchinger, A. H. Crevenna, D. C. Lamb (B03), T. Liedl (A06)
ACS Nano, 2017, 11 (11), pp 11264-11272, DOI: 10.1021/acsnano.7b05631

"Protein-mediated RNA folding governs sequence-specific interactions between rotavirus genome segments"
A. Borodavka, E. C. Dykeman, W. Schrimpf, D. C. Lamb (B03)
Elife, 2017, 6, DOI: 10.7554/eLife.27453

"3D motion of vesicles along microtubules helps them to circumvent obstacles in cells"
I. Verdeny-Vilanova, F. Wehnekamp, N. Mohan, A. S. Alvarez, J. S. Borbely, J. J. Otterstrom, D. C. Lamb (B03), M. Lakadamyali
Journal of Cell Science, 2017, 130 (11), pp 1904-1916, DOI: 10.1242/jcs.201178

"Arbitrary-Region Raster Image Correlation Spectroscopy"
J. Hendrix, T. Dekens, W. Schrimpf, D. C. Lamb (B03)
Biophysical Journal, 2016, 111 (8), pp 1785-1796, DOI: 10.1016/j.bpj.2016.09.012

"Investigation of the Co-Dependence of Morphology and Fluorescence Lifetime in a Metal-Organic Framework"
W. Schrimpf, G. Ossato, P. Hirschle, S. Wuttke, D. C. Lamb (B03)
Small, 2016, 12 (27), pp 3651-3657, DOI: 10.1002/smll.201600619

"Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand"
D. J. Lee, E. Kessel, D. Edinger, D. He, P. M. Klein, L. V. von Voithenberg, D. C. Lamb (B03), U. Lachelt, T. Lehto, E. Wagner (B04)
Biomaterials, 2016, 77, pp 98-110, DOI: 10.1016/j.biomaterials.2015.11.004

"Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers"
J. Hendrix, V. Baumgartel, W. Schrimpf, S. Ivanchenko, M. A. Digman, E. Gratton, H. G. Krausslich, B. Muller, D. C. Lamb (B03)
Journal of Cell Biology, 2015, 210 (4), pp 629-646, DOI: 10.1083/jcb.201504006

"The Lateral Membrane Organization and Dynamics of Myelin Proteins PLP and MBP Are Dictated by Distinct Galactolipids and the Extracellular Matrix"
H. Ozgen, W. Schrimpf, J. Hendrix, J. C. de Jonge, D. C. Lamb (B03), D. Hoekstra, N. Kahya, W. Baron
PLoS One, 2014, 9 (7), DOI: 10.1371/journal.pone.0101834

"Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers"
C. Y. Zhang, P. Kos, K. Muller, W. Schrimpf, C. Troiber, U. Lachelt, C. Scholz, D. C. Lamb (B03), E. Wagner (B04)
Journal of Controlled Release, 2014, 180, pp 42-50, DOI: 10.1016/j.jconrel.2014.02.015

"Implementation and Application of Pulsed Interleaved Excitation for Dual-Color FCS and RICS"
J. Hendrix, D. C. Lamb (B03)
book chapter to appear in Fluorescence Spectroscopy and Microscopy: Methods and Protocols, 2014, 1076, pp 653-682, DOI: 10.1007/978-1-62703-649-8_30

"Pulsed Interleaved Excitation Fluctuation Imaging"
J. Hendrix, W. Schrimpf, M. Holler, D. C. Lamb (B03)
Biophysical Journal, 2013, 105 (4), pp 848-861, DOI: 10.1016/j.bpj.2013.05.059

"Three-dimensional single-particle tracking in live cells: news from the third dimension"
A. Dupont, M. Gorelashvili, V. Schuller, F. Wehnekamp, D. Arcizet, Y. Katayama, D. C. Lamb (B03), D. Heinrich
New Journal of Physics, 2013, 15, DOI: 10.1088/1367-2630/15/7/075008

"Tracking Image Correlation: Combining Single-Particle Tracking and Image Correlation"
A. Dupont, K. Stirnnagel, D. Lindemann, D. C. Lamb (B03)
Biophysical Journal, 2013, 104 (11), pp 2373-2382, DOI: 10.1016/j.bpj.2013.04.005

B04

"Targeting nucleic acid-based therapeutics to tumors: Challenges and strategies for polyplexes"
V. C. Vetter, E. Wagner (B04)
Journal of Controlled Release, 2022, 346, pp 110-135, DOI: 10.1016/j.jconrel.2022.04.013

"The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy"
C. Kitzberger, R. Spellerberg, V. Morath, N. Schwenk, K. A. Schmohl, C. Schug, S. Urnauer, M. Tutter, M. Eiber, F. Schilling, W. A. Weber, S. Ziegler, P. Bartenstein, E. Wagner (B04), P. J. Nelson, C. Spitzweg
Ejnmmi Research, 2022, 12 (1), DOI: 10.1186/s13550-022-00888-w

"Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes"
R. Spellerberg, T. Benli-Hoppe, C. Kitzberger, S. Berger, K. A. Schmohl, N. Schwenk, H. Y. Yen, C. Zach, F. Schilling, W. A. Weber, R. E. Kalin, R. Glass, P. J. Nelson, E. Wagner (B04), C. Spitzweg
Molecular Therapy-Oncolytics, 2021, 23, pp 432-446, DOI: 10.1016/j.omto.2021.10.011

"Cross-Linkable Polyion Complex Micelles from Polypept(o)ide-Based ABC-Triblock Copolymers for siRNA Delivery"
L. Capeloa, M. Yazdi, H. Y. Zhang, X. B. Chen, Y. Nie, E. Wagner (B04), U. Lachelt, M. Barz
Macromolecular Rapid Communications, 2021, DOI: 10.1002/marc.202100698

"Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer"
A. K. Levacic, S. Berger, J. Muller, A. Wegner, U. Lachelt, C. Dohmen, C. Rudolph, E. Wagner (B04)
Journal of Controlled Release, 2021, 339, pp 27-40, DOI: 10.1016/j.jconrel.2021.09.016

"Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence-Defined Components"
T. Benli-Hoppe, S. G. Ozturk, O. Ozturk, S. Berger, E. Wagner (B04), M. Yazdi
Macromolecular Rapid Communications, 2021, DOI: 10.1002/marc.202100602

"Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release"
S. Berger, A. K. Levacic, E. Horterer, U. Wilk, T. Benli-Hoppe, Y. F. Wang, O. Ozturk, J. Luo, E. Wagner (B04)
Biomacromolecules, 2021, 22 (3), pp 1282-1296, DOI: 10.1021/acs.biomac.0c01779

"Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors"
C. von Schirnding, I. Giopanou, A. Hermawan, L. Wehl, G. Ntaliarda, B. Illes, S. Datz, F. Geisslinger, K. Bartel, A. K. Sommer, M. Lianou, V. Weiss, J. Feckl, A. M. Vollmar, C. Brauchle, G. T. Stathopoulos, E. Wagner (B04), A. Roidl, T. Bein (B05), H. Engelke (B11)
Chem, 2021, 7 (2), pp 480-494, DOI: 10.1016/j.chempr.2020.11.021

"Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach"
F. Freitag, E. Wagner (B04)
Advanced Drug Delivery Reviews, 2021, 168, pp 30-54, DOI: 10.1016/j.addr.2020.03.005

"Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors"
J. Luo, J. Schmaus, M. C. Cui, E. Horterer, U. Wilk, M. Hohn, M. Dather, S. Berger, T. Benli-Hoppe, L. Peng, E. Wagner (B04)
Journal of Controlled Release, 2021, 329, pp 919-933, DOI: 10.1016/j.jconrel.2020.10.022

"Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform"
D. M. Loy, R. Krzyszton, U. Lachelt, J. O. Rädler (A07&B01), E. Wagner (B04)
Processes, 2021, 9 (1), DOI: 10.3390/pr9010129

"Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization"
Y. F. Wang, E. Wagner (B04)
Pharmaceutics, 2020, 12 (9), DOI: 10.3390/pharmaceutics12090888

"Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles"
L. Haddick, W. Zhang, S. Reinhard, K. Moller, H. Engelke (B11), E. Wagner (B04), T. Bein (B05)
Pharmaceutics, 2020, 12 (6), DOI: 10.3390/pharmaceutics12060505

"Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides"
J. Kuhn, Y. Lin, A. K. Levacic, N. Al Danaf, L. Peng, M. Hohn, D. C. Lamb (B03), E. Wagner (B04), U. Lachelt
Bioconjugate Chemistry, 2020, 31 (3), pp 729-742, DOI: 10.1021/acs.bioconjchem.9b00853

"Artificial peptides for antitumoral siRNA delivery"
J. Luo, E. Wagner (B04), Y. F. Wang
Journal of Materials Chemistry B, 2020, 8 (10), pp 2020-2031, DOI: 10.1039/c9tb02756d

"Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells"
Y. F. Wang, J. Luo, I. Truebenbach, S. Reinhard, P. M. Klein, M. Hohn, S. Kern, S. Morys, D. M. Loy, E. Wagner (B04), W. Zhang
Acs Biomaterials Science & Engineering, 2020, 6 (2), pp 1074-1089, DOI: 10.1021/acsbiomaterials.9b01904

"Supramolecular Assembly of Aminoethylene-Lipopeptide PMO Conjugates into RNA Splice-Switching Nanomicelles"
J. Kuhn, P. M. Klein, N. Al Danaf, J. Z. Nordin, S. Reinhard, D. M. Loy, M. Hohn, S. El Andaloussi, D. C. Lamb (B03), E. Wagner (B04), Y. Aoki, T. Lehto, U. Lachelt
Advanced Functional Materials, 2019, 29 (48), DOI: 10.1002/adfm.201906432

"Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A"
B. Ljepoja, C. Schreiber, F. A. Gegenfurtner, J. Garcia-Roman, B. Kohler, S. Zahler (B08), J. O. Rädler (A07&B01), E. Wagner (B04), A. Roidl
PLoS One, 2019, 14 (11), DOI: 10.1371/journal.pone.0224314

"A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure-activity relationship"
D. M. Loy, P. M. Klein, R. Krzysztoń, U. Lächelt, J. O. Rädler (A07&B01), E. Wagner (B04)
PeerJ Materials Science, 2019, 1, p pp e1, DOI: 10.7717/peerj-matsci.1

"Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions"
L. Peng, E. Wagner (B04)
Biomacromolecules, 2019, 20 (10), pp 3613-3626, DOI: 10.1021/acs.biomac.9b00999

"Downregulation of GRK5 hampers the migration of breast cancer cells"
A. K. Sommer, M. Falcenberg, B. Ljepoja, T. Frohlich, G. J. Arnold, E. Wagner (B04), A. Roidl
Scientific Reports, 2019, 9, DOI: 10.1038/s41598-019-51923-1

"Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells"
I. Truebenbach, W. Zhang, Y. F. Wang, S. Kern, M. Hohn, S. Reinhard, J. Gorges, U. Kazmaier, E. Wagner (B04)
International Journal of Pharmaceutics, 2019, 569, DOI: 10.1016/j.ijpharm.2019.118570

"IL4-Receptor-Targeted Dual Antitumoral Apoptotic Peptide-siRNA Conjugate Lipoplexes"
J. Luo, M. Hohn, S. Reinhard, D. M. Loy, P. M. Klein, E. Wagner (B04)
Advanced Functional Materials, 2019, 29 (25), DOI: 10.1002/adfm.201900697

"Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy"
L. Pfitzer, C. Moser, F. Gegenfurtner, A. Arner, F. Foerster, C. Atzberger, T. Zisis, R. Kubisch-Dohmen, J. Busse, R. Smith, G. Timinszky, O. V. Kalinina, R. Muller, E. Wagner (B04), A. M. Vollmar, S. Zahler (B08)
Cell Death & Disease, 2019, 10, DOI: 10.1038/s41419-019-1546-9

"Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface"
A. Zimpel, N. Al Danaf, B. Steinborn, J. Kuhn, M. Hohn, T. Bauer, P. Hirschle, W. Schrimpf, H. Engelke (B11), E. Wagner (B04), M. Barz, D. C. Lamb (B03), U. Lachelt, S. Wuttke
ACS Nano, 2019, 13 (4), pp 3884-3895, DOI: 10.1021/acsnano.8b06287

"MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators"
B. Ljepoja, J. Garcia-Roman, A. K. Sommer, E. Wagner (B04), A. Roidl
Breast, 2019, 43, pp 31-38, DOI: 10.1016/j.breast.2018.10.007

"Sequence-Defined Cationic Lipo-Oligomers Containing Unsaturated Fatty Acids for Transfection"
S. Reinhard, E. Wagner (B04)
book chapter to appear in NANOTECHNOLOGY FOR NUCLEIC ACID DELIVERY: Methods and Protocols, 2019, 1943, pp 1-25, DOI: 10.1007/978-1-4939-9092-4_1

"Combinatorial siRNA Polyplexes for Receptor Targeting"
D. J. Lee, E. Wagner (B04)
book chapter to appear in Rna Interference and Cancer Therapy: Methods and Protocols, 2019, 1974, pp 83-98, DOI: 10.1007/978-1-4939-9220-1_7

"Click-Shielded and Targeted Lipopolyplexes"
P. M. Klein, E. Wagner (B04)
book chapter to appear in Oligonucleotide-Based Therapies: Methods and Protocols, 2019, 2036, pp 141-164, DOI: 10.1007/978-1-4939-9670-4_8

"Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes"
S. Reinhard, Y. F. Wang, S. Dengler, E. Wagner (B04)
Bioconjugate Chemistry, 2018, 29 (11), pp 3649-3657, DOI: 10.1021/acs.bioconjchem.8b00585

"Bioresponsive polyplexes - chemically programmed for nucleic acid delivery"
S. Hager, E. Wagner (B04)
Expert Opinion on Drug Delivery, 2018, 15 (11), pp 1067-1083, DOI: 10.1080/17425247.2018.1526922

"Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo"
P. M. Klein, S. Kern, D. J. Lee, J. Schmaus, M. Hohn, J. Gorges, U. Kazmaier, E. Wagner (B04)
Biomaterials, 2018, 178, pp 630-642, DOI: 10.1016/j.biomaterials.2018.03.031

"Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery"
B. Steinborn, I. Truebenbach, S. Morys, U. Lachelt, E. Wagner (B04), W. Zhang
Journal of Gene Medicine, 2018, 20 (7-8), DOI: 10.1002/jgm.3041

"A proteomic analysis of an in vitro knock-out of miR-200c"
B. Ljepoja, J. Garcia-Roman, A. K. Sommer, T. Frohlich, G. J. Arnold, E. Wagner (B04), A. Roidl
Scientific Reports, 2018, 8, DOI: 10.1038/s41598-018-25240-y

"EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent"
S. Morys, S. Urnauer, C. Spitzweg, E. Wagner (B04)
Macromolecular Bioscience, 2018, 18 (1), DOI: 10.1002/mabi.201700203

"Solid-phase supported design of carriers for therapeutic nucleic acid delivery"
A. K. Levacic, S. Morys, E. Wagner (B04)
Bioscience Reports, 2017, 37, DOI: 10.1042/BSR20160617

"Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes"
A. K. Levacic, S. Morys, S. Kempter, U. Lachelt, E. Wagner (B04)
Human Gene Therapy, 2017, 28 (10), pp 862-874, DOI: 10.1089/hum.2017.123

"Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia"
D. J. Lee, E. Kessel, T. Lehto, X. Y. Liu, N. Yoshinaga, K. Padari, Y. C. Chen, S. Kempter, S. Uchida, J. O. Rädler (A07&B01), M. Pooga, M. T. Sheu, K. Kataoka, E. Wagner (B04)
Bioconjugate Chemistry, 2017, 28 (9), pp 2393-2409, DOI: 10.1021/acs.bioconjchem.7b00383

"Polymeric micelles self-assembled from amphiphilic polymers with twin disulfides used as siRNA carriers to enhance the transfection"
C. Y. Zhang, S. Y. Peng, B. Zhao, W. J. Luo, L. J. Zhang
Materials Science & Engineering C-Materials for Biological Applications, 2017, 78, pp 546-552, DOI: 10.1016/j.msec.2017.04.039

"Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers"
S. Reinhard, W. Zhang, E. Wagner (B04)
ChemMedChem, 2017, 12 (17), pp 1464-1470, DOI: 10.1002/cmdc.201700350

"Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery"
P. Zhang, B. Steinborn, U. Lachelt, S. Zahler (B08), E. Wagner (B04)
Biomacromolecules, 2017, 18 (8), pp 2509-2520, DOI: 10.1021/acs.biomac.7b00666

"Polyplex Evolution: Understanding Biology, Optimizing Performance"
A. Hall, U. Lachelt, J. Bartek, E. Wagner (B04), S. M. Moghimi
Molecular Therapy, 2017, 25 (7), pp 1476-1490, DOI: 10.1016/j.ymthe.2017.01.024

"Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles"
R. Krzyszton, B. Salem, D. J. Lee, G. Schwake, E. Wagner (B04), J. O. Rädler (A07&B01)
Nanoscale, 2017, 9 (22), pp 7442-7453, DOI: 10.1039/c7nr01593c

"Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks"
R. Roder, T. Preiss, P. Hirschle, B. Steinborn, A. Zimpel, M. Hohn, J. O. Rädler (A07&B01), T. Bein (B05), E. Wagner (B04), S. Wuttke, U. Lachelt
Journal of the American Chemical Society, 2017, 139 (6), pp 2359-2368, DOI: 10.1021/jacs.6b11934

"How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides"
S. Reinhard, E. Wagner (B04)
Macromolecular Bioscience, 2017, 17 (1), DOI: 10.1002/mabi.201600152

"Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes"
D. J. Lee, D. S. He, E. Kessel, K. Padari, S. Kempter, U. Lachelt, J. O. Rädler (A07&B01), M. Pooga, E. Wagner (B04)
Journal of Controlled Release, 2016, 244, pp 280-291, DOI: 10.1016/j.jconrel.2016.06.011

"Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes"
P. M. Klein, S. Reinhard, D. J. Lee, K. Muller, D. Ponader, L. Hartmann, E. Wagner (B04)
Nanoscale, 2016, 8 (42), pp 18098-18104, DOI: 10.1039/c6nr05767e

"EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery"
K. Muller, P. M. Klein, P. Heissig, A. Roidl, E. Wagner (B04)
Nanotechnology, 2016, 27 (46), DOI: 10.1088/0957-4484/27/46/464001

"Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases"
A. K. Sommer, A. Hermawan, F. M. Mickler, B. Ljepoja, P. Knyazev, C. Brauchle, A. Ullrich, E. Wagner (B04), A. Roidl
Oncotarget, 2016, 7 (31), pp 50461-50476, DOI: 10.18632/oncotarget.10459

"Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery"
K. Muller, E. Kessel, P. M. Klein, M. Hohn, E. Wagner (B04)
Molecular Pharmaceutics, 2016, 13 (7), pp 2332-2345, DOI: 10.1021/acs.molpharmaceut.6b00102

"Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell"
W. Zhang, K. Muller, E. Kessel, S. Reinhard, D. S. He, P. M. Klein, M. Hohn, W. Rodl, S. Kempter, E. Wagner (B04)
Advanced Healthcare Materials, 2016, 5 (12), pp 1493-1504, DOI: 10.1002/adhm.201600057

"Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration"
C. Schreiber, F. J. Segerer, E. Wagner (B04), A. Roidl, J. O. Rädler (A07&B01)
Scientific Reports, 2016, 6, DOI: 10.1038/srep26858

"Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers"
A. Zimpel, T. Preiss, R. Roder, H. Engelke (B11), M. Ingrisch, M. Peller, J. O. Rädler (A07&B01), E. Wagner (B04), T. Bein (B05), U. Lachelt, S. Wuttke
Chemistry of Materials, 2016, 28 (10), pp 3318-3326, DOI: 10.1021/acs.chemmater.6b00180

"DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization"
P. Heissig, P. M. Klein, P. Hadwiger, E. Wagner (B04)
Molecular Therapy-Nucleic Acids, 2016, 5, DOI: 10.1038/mtna.2016.6

"Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand"
D. J. Lee, E. Kessel, D. Edinger, D. He, P. M. Klein, L. V. von Voithenberg, D. C. Lamb (B03), U. Lachelt, T. Lehto, E. Wagner (B04)
Biomaterials, 2016, 77, pp 98-110, DOI: 10.1016/j.biomaterials.2015.11.004

"Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps"
K. Moller, K. Muller, H. Engelke (B11), C. Brauchle, E. Wagner (B04), T. Bein (B05)
Nanoscale, 2016, 8 (7), pp 4007-4019, DOI: 10.1039/c5nr06246b

"Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes"
P. M. Klein, K. Muller, C. Gutmann, P. Kos, A. K. Levacic, D. Edinger, M. Huhn, J. C. Leroux, M. A. Gauthier, E. Wagner (B04)
Journal of Controlled Release, 2015, 205, pp 109-119, DOI: 10.1016/j.jconrel.2014.12.035

"Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key"
E. Wagner
Angewandte Chemie-International Edition, 2015, 54 (20), pp 5824-5826, DOI: 10.1002/anie.201502146

"Sequence-Defined Oligoaminoamides for the Delivery of siRNAs"
D. J. Lee, E. Wagner (B04), T. Lehto
book chapter to appear in Regulatory Non-Coding Rnas: Methods and Protocols, 2015, 1206, pp 15-27, DOI: 10.1007/978-1-4939-1369-5_2

"Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells"
F. Kopp, A. Hermawan, P. S. Oak, V. K. Ulaganathan, A. Herrmann, N. Elnikhely, C. Thakur, Z. G. Xiao, P. Knyazev, B. Ataseven, R. Savai, E. Wagner (B04), A. Roidl
Translational Oncology, 2014, 7 (6), pp 702-711, DOI: 10.1016/j.tranon.2014.09.002

"The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility"
M. H. Menhofer, R. Kubisch, L. Schreiner, M. Zorn, F. Foerster, R. Mueller, J. O. Rädler (A07&B01), E. Wagner (B04), A. M. Vollmar, S. Zahler (B08)
PLoS One, 2014, 9 (11), DOI: 10.1371/journal.pone.0112542

"Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection"
P. M. Klein, E. Wagner (B04)
Antioxidants & Redox Signaling, 2014, 21 (5), pp 804-817, DOI: 10.1089/ars.2013.5714

"Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers"
C. Y. Zhang, P. Kos, K. Muller, W. Schrimpf, C. Troiber, U. Lachelt, C. Scholz, D. C. Lamb (B03), E. Wagner (B04)
Journal of Controlled Release, 2014, 180, pp 42-50, DOI: 10.1016/j.jconrel.2014.02.015

"Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration"
F. Kopp, A. Hermawan, P. S. Oak, A. Herrmann, E. Wagner (B04), A. Roidl
Molecular Cancer, 2014, 13, DOI: 10.1186/1476-4598-13-16

"The proto-oncogene KRAS is targeted by miR-200c"
F. Kopp, E. Wagner (B04), A. Roidl
Oncotarget, 2014, 5 (1), pp 185-195, DOI: 10.18632/oncotarget.1427

"Sequence-defined polymers for the delivery of oligonucleotides"
T. Lehto, E. Wagner (B04)
Nanomedicine, 2014, 9 (18), pp 2843-2859, DOI: 10.2217/NNM.14.166

"Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes"
C. Troiber, D. Edinger, P. Kos, L. Schreiner, R. Klager, A. Herrmann, E. Wagner (B04)
Biomaterials, 2013, 34 (5), pp 1624-1633, DOI: 10.1016/j.biomaterials.2012.11.021

"Biomaterials in RNAi therapeutics: quo vadis?"
E. Wagner
Biomaterials Science, 2013, 1 (8), pp 804-809, DOI: 10.1039/c3bm60071h

"miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression"
F. Kopp, P. S. Oak, E. Wagner (B04), A. Roidl
PLoS One, 2012, 7 (11), DOI: 10.1371/journal.pone.0050469

B05

"Mesoporous Biodegradable Magnesium Phosphate-Citrate Nanocarriers Amplify Methotrexate Anticancer Activity in HeLa Cells"
L. Wehl, C. von Schirnding, M. C. Bayer, O. Zhuzhgova, H. Engelke (B11), T. Bein
Bioconjugate Chemistry, 2022, 33 (4), pp 566-575, DOI: 10.1021/acs.bioconjchem.1c00565

"Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice"
J. Wagner, D. Gossl, N. Ustyanovska, M. Y. Xiong, D. Hauser, O. Zhuzhgova, S. Hocevar, B. Taskoparan, L. Poller, S. Datz, H. Engelke (B11), Y. Daali, T. Bein (B05), C. Bourquin
ACS Nano, 2021, 15 (3), pp 4450-4466, DOI: 10.1021/acsnano.0c08384

"Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors"
C. von Schirnding, I. Giopanou, A. Hermawan, L. Wehl, G. Ntaliarda, B. Illes, S. Datz, F. Geisslinger, K. Bartel, A. K. Sommer, M. Lianou, V. Weiss, J. Feckl, A. M. Vollmar, C. Brauchle, G. T. Stathopoulos, E. Wagner (B04), A. Roidl, T. Bein (B05), H. Engelke (B11)
Chem, 2021, 7 (2), pp 480-494, DOI: 10.1016/j.chempr.2020.11.021

"Curcumin Encapsulated in Crosslinked Cyclodextrin Nanoparticles Enables Immediate Inhibition of Cell Growth and Efficient Killing of Cancer Cells"
K. Moller, B. Macaulay, T. Bein (B05)
Nanomaterials, 2021, 11 (2), DOI: 10.3390/nano11020489

"Organ-Restricted Vascular Delivery of Nanoparticles for Lung Cancer Therapy"
D. A. Bolukbas, S. Datz, C. Meyer-Schwickerath, C. Morrone, A. Doryab, D. Gossl, M. Vreka, L. Yang, C. Argyo, S. H. van Rijt, M. Lindner, O. Eickelberg, T. Stoeger, O. Schmid, S. Lindsted, G. T. Stathopoulos, T. Bein (B05), D. E. Wagner (B04), S. Meiners
Advanced Therapeutics, 2020, 3 (7), DOI: 10.1002/adtp.202000017

"Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles"
L. Haddick, W. Zhang, S. Reinhard, K. Moller, H. Engelke (B11), E. Wagner (B04), T. Bein (B05)
Pharmaceutics, 2020, 12 (6), DOI: 10.3390/pharmaceutics12060505

"Degradable Drug Carriers: Vanishing Mesoporous Silica Nanoparticles"
K. Moller, T. Bein (B05)
Chemistry of Materials, 2019, 31 (12), pp 4364-4378, DOI: 10.1021/acs.chemmater.9b00221

"Highly active enzymes immobilized in large pore colloidal mesoporous silica nanoparticles"
D. Gossl, H. Singer, H. Y. Chiu, A. Schmidt, M. Lichtnecker, H. Engelke (B11), T. Bein (B05)
New Journal of Chemistry, 2019, 43 (4), pp 1671-1680, DOI: 10.1039/c8nj04585b

"Biocompatible crosslinked -cyclodextrin nanoparticles as multifunctional carriers for cellular delivery"
S. Datz, B. Illes, D. Gossl, C. V. Schirnding, H. Engelke (B11), T. Bein (B05)
Nanoscale, 2018, 10 (34), pp 16284-16292, DOI: 10.1039/c8nr02462f

"Clickable Multifunctional Large-Pore Mesoporous Silica Nanoparticles as Nanocarriers"
H. Y. Chiu, D. Goss, L. Haddick, H. Engelke (B11), T. Bein (B05)
Chemistry of Materials, 2018, 30 (3), pp 644-654, DOI: 10.1021/acs.chemmater.7b03472

"Nanoparticle mediated delivery and small molecule triggered activation of proteins in the nucleus"
H. Y. Chiu, J. A. Bates, J. Helma, H. Engelke (B11), H. Harz, T. Bein (B05), H. Leonhardt
Nucleus, 2018, 9 (1), pp 530-542, DOI: 10.1080/19491034.2018.1523665

"Synthesis and Functionalization of Ordered Large-Pore Mesoporous Silica Nanoparticles for Biomedical Applications"
H. Y. Chiu, H. Leonhardt, T. Bein (B05)
Chemie Ingenieur Technik, 2017, 89 (7), pp 876-886, DOI: 10.1002/cite.201700021

"Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks"
R. Roder, T. Preiss, P. Hirschle, B. Steinborn, A. Zimpel, M. Hohn, J. O. Rädler (A07&B01), T. Bein (B05), E. Wagner (B04), S. Wuttke, U. Lachelt
Journal of the American Chemical Society, 2017, 139 (6), pp 2359-2368, DOI: 10.1021/jacs.6b11934

"Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications"
S. Wuttke, A. Zimpel, T. Bein (B05), S. Braig, K. Stoiber, A. Vollmar, D. Muller, K. Haastert-Talini, J. Schaeske, M. Stiesch, G. Zahn, A. Mohmeyer, P. Behrens, O. Eickelberg, D. A. Bolukbas, S. Meiners
Advanced Healthcare Materials, 2017, 6 (2), DOI: 10.1002/adhm.201600818

"Talented Mesoporous Silica Nanoparticles"
K. Moller, T. Bein (B05)
Chemistry of Materials, 2017, 29 (1), pp 371-388, DOI: 10.1021/acs.chemmater.6b03629

"Lipid bilayer-coated curcumin-based mesoporous organosilica nanoparticles for cellular delivery"
S. Datz, H. Engelke (B11), C. V. Schirnding, L. Nguyen, T. Bein (B05)
Microporous and Mesoporous Materials, 2016, 225, pp 371-377, DOI: 10.1016/j.micromeso.2015.12.006

"Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time"
H. Y. Chiu, W. Deng, H. Engelke (B11), J. Helma, H. Leonhardt, T. Bein (B05)
Scientific Reports, 2016, 6, DOI: 10.1038/srep25019

"Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers"
A. Zimpel, T. Preiss, R. Roder, H. Engelke (B11), M. Ingrisch, M. Peller, J. O. Rädler (A07&B01), E. Wagner (B04), T. Bein (B05), U. Lachelt, S. Wuttke
Chemistry of Materials, 2016, 28 (10), pp 3318-3326, DOI: 10.1021/acs.chemmater.6b00180

"A Selective Mucin/Methylcellulose Hybrid Gel with Tailored Mechanical Properties"
C. Nowald, A. Penk, H. Y. Chiu, T. Bein (B05), D. Huster, O. Lieleg (B07)
Macromolecular Bioscience, 2016, 16 (4), pp 567-579, DOI: 10.1002/mabi.201500353

"Efficient functionalization of mesoporous MCM-41 with aromatic organo-lithium reagents"
A. Schmidt, P. Kostler, F. Tambornino, T. Bein (B05)
Microporous and Mesoporous Materials, 2016, 223, pp 219-224, DOI: 10.1016/j.micromeso.2015.10.015

"A molecular nanocap activated by superparamagnetic heating for externally stimulated cargo release"
B. Ruhle, S. Datz, C. Argyo, T. Bein (B05), J. I. Zink
Chemical Communications, 2016, 52 (9), pp 1843-1846, DOI: 10.1039/c5cc08636a

"Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery"
S. Heidegger, D. Gossl, A. Schmidt, S. Niedermayer, C. Argyo, S. Endres, T. Bein (B05), C. Bourquin
Nanoscale, 2016, 8 (2), pp 938-948, DOI: 10.1039/c5nr06122a

"Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps"
K. Moller, K. Muller, H. Engelke (B11), C. Brauchle, E. Wagner (B04), T. Bein (B05)
Nanoscale, 2016, 8 (7), pp 4007-4019, DOI: 10.1039/c5nr06246b

"Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release"
S. Datz, C. Argyo, M. Gattner, V. Weiss, K. Brunner, J. Bretzler, C. von Schirnding, A. A. Torrano, F. Spada, M. Vrabel, H. Engelke (B11), C. Brauchle, T. Carell (A05), T. Bein (B05)
Nanoscale, 2016, 8 (15), pp 8101-8110, DOI: 10.1039/c5nr08163g

"MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells"
S. Wuttke, S. Braig, T. Preiss, A. Zimpel, J. Sicklinger, C. Bellomo, J. O. Rädler (A07&B01), A. M. Vollmar, T. Bein (B05)
Chemical Communications, 2015, 51 (87), pp 15752-15755, DOI: 10.1039/c5cc06767g

"Lipid-bilayer coated nanosized bimodal mesoporous carbon spheres for controlled release applications"
B. Mandlmeier, S. Niedermayer, A. Schmidt, J. Schuster, T. Bein (B05)
Journal of Materials Chemistry B, 2015, 3 (48), pp 9323-9329, DOI: 10.1039/c5tb01635e

B07

"A Selective Mucin/Methylcellulose Hybrid Gel with Tailored Mechanical Properties"
C. Nowald, A. Penk, H. Y. Chiu, T. Bein (B05), D. Huster, O. Lieleg (B07)
Macromolecular Bioscience, 2016, 16 (4), pp 567-579, DOI: 10.1002/mabi.201500353

"Modulating Mucin Hydration and Lubrication by Deglycosylation and Polyethylene Glycol Binding"
T. Crouzier, K. Boettcher, A. R. Geonnotti, N. L. Kavanaugh, J. B. Hirsch, K. Ribbeck, O. Lieleg (B07)
Advanced Materials Interfaces, 2015, 2 (18), DOI: 10.1002/admi.201500308

"Enzymatically active biomimetic micropropellers for the penetration of mucin gels"
D. Walker, B. T. Kasdorf, H. H. Jeong, O. Lieleg (B07), P. Fischer
Science Advances, 2015, 1 (11), DOI: 10.1126/sciadv.1500501

"The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel"
F. Arends, C. Nowald, K. Pflieger, K. Boettcher, S. Zahler (B08), O. Lieleg (B07)
PLoS One, 2015, 10 (2), DOI: 10.1371/journal.pone.0118090

"A microfluidics approach to study the accumulation of molecules at basal lamina interfaces"
F. Arends, S. Sellner, P. Seifert, U. Gerland (A03), M. Rehberg (B10), O. Lieleg (B07)
Lab on a Chip, 2015, 15 (16), pp 3326-3334, DOI: 10.1039/c5lc00561b

"Ion-Specific Effects Modulate the Diffusive Mobility of Colloids in an Extracellular Matrix Gel"
F. Arends, R. Baumgartel, O. Lieleg (B07)
Langmuir, 2013, 29 (51), pp 15965-15973, DOI: 10.1021/la404016y

B08

"Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration"
T. Zisis, D. B. Bruckner, T. Brandstatter, W. X. Siow, J. d'Alessandro, A. M. Vollmar, C. P. Broedersz (B12), S. Zahler (B08)
Biophysical Journal, 2022, 121 (1), pp 44-60, DOI: 10.1016/j.bpj.2021.12.006

"Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds"
C. A. Karg, S. J. Wang, N. Al Danaf, R. P. Pemberton, D. Bernard, M. Kretschmer, S. Schneider (A12), T. Zisis, A. M. Vollmar, D. C. Lamb (B03), S. Zahler (B08), S. Moser
Angewandte Chemie-International Edition, 2021, 60 (41), pp 22578-22584, DOI: 10.1002/anie.202107813

"Mechanical Aspects of Angiogenesis"
M. Kretschmer, D. Ruediger, S. Zahler (B08)
Cancers, 2021, 13 (19), DOI: 10.3390/cancers13194987

"Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control"
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R. Chait, R. Hauschild, J. Lange, C. Guet, M. Sixt, S. Zahler (B08)
Acs Applied Materials & Interfaces, 2021, 13 (30), pp 35545-35560, DOI: 10.1021/acsami.1c09850

"Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids"
B. Illes, A. Fuchs, F. Gegenfurtner, E. Ploetz, S. Zahler (B08), A. M. Vollmar, H. Engelke (B11)
iScience, 2021, 24 (3), DOI: 10.1016/j.isci.2021.102185

"Cell-Based Strain Remodeling of a Nonfibrous Matrix as an Organizing Principle for Vasculogenesis"
D. Rudiger, K. Kick, A. Goychuk, A. M. Vollmar, E. Frey (B02), S. Zahler (B08)
Cell Reports, 2020, 32 (6), DOI: 10.1016/j.celrep.2020.108015

"Optical Manipulation of F-Actin with Photoswitchable Small Molecules"
M. Borowiak, F. Kullmer, F. Gegenfurtner, S. Peil, V. Nasufovic, S. Zahler (B08), O. Thorn-Seshold (B09), D. Trauner (B09), H. D. Arndt
Journal of the American Chemical Society, 2020, 142 (20), pp 9240-9249, DOI: 10.1021/jacs.9b12898

"Metal-Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH"
E. Ploetz, A. Zimpel, V. Cauda, D. Bauer, D. C. Lamb (B03), C. Haisch, S. Zahler (B08), A. M. Vollmar, S. Wuttke, H. Engelke (B11)
Advanced Materials, 2020, 32 (19), p pp 8, DOI: 10.1002/adma.201907267

"Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A"
B. Ljepoja, C. Schreiber, F. A. Gegenfurtner, J. Garcia-Roman, B. Kohler, S. Zahler (B08), J. O. Rädler (A07&B01), E. Wagner (B04), A. Roidl
PLoS One, 2019, 14 (11), DOI: 10.1371/journal.pone.0224314

"Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels"
F. Geiger, D. Rudiger, S. Zahler (B08), H. Engelke (B11)
PLoS One, 2019, 14 (11), DOI: 10.1371/journal.pone.0225215

"Chivosazole A Modulates Protein Protein Interactions of Actin"
S. J. Wang, F. A. Gegenfurtner, A. H. Crevenna, C. Ziegenhain, Z. Kliesmete, W. Enard, R. Muller, A. M. Vollmar, S. Schneider, S. Zahler (B08)
Journal of Natural Products, 2019, 82 (7), pp 1961-1970, DOI: 10.1021/acs.jnatprod.9b00335

"Actin stabilizing compounds show specific biological effects due to their binding mode"
S. J. Wang, A. H. Crevenna, I. Ugur, A. Marion, I. Antes, U. Kazmaier, M. Hoyer, D. C. Lamb (B03), F. Gegenfurtner, Z. Kliesmetes, C. Ziegenhain, W. Enard, A. Vollmar, S. Zahler (B08)
Scientific Reports, 2019, 9, DOI: 10.1038/s41598-019-46282-w

"Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy"
L. Pfitzer, C. Moser, F. Gegenfurtner, A. Arner, F. Foerster, C. Atzberger, T. Zisis, R. Kubisch-Dohmen, J. Busse, R. Smith, G. Timinszky, O. V. Kalinina, R. Muller, E. Wagner (B04), A. M. Vollmar, S. Zahler (B08)
Cell Death & Disease, 2019, 10, DOI: 10.1038/s41419-019-1546-9

"Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone"
F. A. Gegenfurtner, T. Zisis, N. Al Danaf, W. Schrimpf, Z. Kliesmete, C. Ziegenhain, W. Enard, U. Kazmaier, D. C. Lamb (B03), A. M. Vollmar, S. Zahler (B08)
Cellular and Molecular Life Sciences, 2018, 75 (24), pp 4539-4555, DOI: 10.1007/s00018-018-2919-4

"Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils"
Y. Yordanova, W. Vanderlinden, R. Stoll, D. Rudiger, A. Tosstorff, W. Zaremba, G. Winter, S. Zahler (B08), W. Friess
Scientific Reports, 2018, 8, DOI: 10.1038/s41598-018-29529-w

"Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing"
F. A. Gegenfurtner, B. Jahn, H. Wagner, C. Ziegenhain, W. Enard, L. Geistlinger, J. O. Rädler (A07&B01), A. M. Vollmar, S. Zahler (B08)
Journal of Cell Science, 2018, 131 (10), DOI: 10.1242/jcs.212886

"Targeting de novo lipogenesis as a novel approach in anti-cancer therapy"
K. Stoiber, O. Naglo, C. Pernpeintner, S. W. Zhang, A. Koeberle, M. Ulrich, O. Werz, R. Muller, S. Zahler (B08), T. Lohmüller (A08), J. Feldmann, S. Braig
British Journal of Cancer, 2018, 118 (1), pp 43-51, DOI: 10.1038/bjc.2017.374

"Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer"
C. Moser, D. Rudiger, F. Forster, J. von Blume, P. Yu, B. Kuster, U. Kazmaier, A. M. Vollmar, S. Zahler (B08)
Scientific Reports, 2017, 7, DOI: 10.1038/s41598-017-16759-7

"Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery"
P. Zhang, B. Steinborn, U. Lachelt, S. Zahler (B08), E. Wagner (B04)
Biomacromolecules, 2017, 18 (8), pp 2509-2520, DOI: 10.1021/acs.biomac.7b00666

"New View on Endothelial Cell Migration Switching Modes of Migration Based on Matrix Composition"
K. Kick, K. Nekolla, M. Rehberg (B10), A. M. Vollmar, S. Zahler (B08)
Arteriosclerosis Thrombosis and Vascular Biology, 2016, 36 (12), pp 2346-2357, DOI: 10.1161/ATVBAHA.116.307870

"Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments"
S. L. Schuster, F. J. Segerer, F. A. Gegenfurtner, K. Kick, C. Schreiber, M. Albert, A. M. Vollmar, J. O. Rädler (A07&B01), S. Zahler (B08)
Biomaterials, 2016, 102, pp 137-147, DOI: 10.1016/j.biomaterials.2016.06.021

"Influence of Surface Modifications on the Spatiotemporal Microdistribution of Quantum Dots In Vivo"
K. Nekolla, K. Kick, S. Sellner, K. Mildner, S. Zahler (B08), D. Zeuschner, F. Krombach (B10), M. Rehberg (B10)
Small, 2016, 12 (19), pp 2641-2651, DOI: 10.1002/smll.201600071

"Versatile method to generate multiple types of micropatterns"
F. J. Segerer, P. J. F. Rottgermann, S. Schuster, A. P. Alberola, S. Zahler (B08), J. O. Rädler (A07&B01)
Biointerphases, 2016, 11 (1), DOI: 10.1116/1.4940703

"Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death"
M. Borowiak, W. Nahaboo, M. Reynders, K. Nekolla, P. Jalinot, J. Hasserodt, M. Rehberg (B10), M. Delattre, S. Zahler (B08), A. Vollmar, D. Trauner (B09), O. Thorn-Seshold
Cell, 2015, 162 (2), pp 403-411, DOI: 10.1016/j.cell.2015.06.049

"The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel"
F. Arends, C. Nowald, K. Pflieger, K. Boettcher, S. Zahler (B08), O. Lieleg (B07)
PLoS One, 2015, 10 (2), DOI: 10.1371/journal.pone.0118090

"The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility"
M. H. Menhofer, R. Kubisch, L. Schreiner, M. Zorn, F. Foerster, R. Mueller, J. O. Rädler (A07&B01), E. Wagner (B04), A. M. Vollmar, S. Zahler (B08)
PLoS One, 2014, 9 (11), DOI: 10.1371/journal.pone.0112542

B09

"SAXS measurements of azobenzene lipid vesicles reveal buffer-dependent photoswitching and quantitative Z -> E isomerisation by X-rays"
M. F. Ober, A. Muller-Deku, A. Baptist, B. Ajanovic, H. Amenitsch, O. Thorn-Seshold (B09), B. Nickel (A07)
Nanophotonics, 2022, 11 (10), pp 2361-2368, DOI: 10.1515/nanoph-2022-0053

"Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically"
J. G. Felber, L. Poczka, K. C. Scholzen, L. Zeisel, M. S. Maier, S. Busker, U. Theisen, C. Brandstadter, K. Becker, E. S. J. Arner, J. Thorn-Seshold, O. Thorn-Seshold (B09)
Nature Communications, 2022, 13 (1), DOI: 10.1038/s41467-022-29136-4

"In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M"
L. Gao, J. C. M. Meiring, A. Varady, I. E. Ruider, C. Heise, M. Wranik, C. D. Velasco, J. A. Taylor, B. Terni, T. Weinert, J. Standfuss, C. C. Cabernard, A. Llobet, M. O. Steinmetz, A. R. Bausch (A10), M. Distel, J. Thorn-Seshold, A. Akhmanova, O. Thorn-Seshold (B09)
Journal of the American Chemical Society, 2022, 144 (12), pp 5614-5628, DOI: 10.1021/jacs.2c01020

"Photoswitchable Epothilone-Based Microtubule Stabilisers Allow GFP-Imaging-Compatible, Optical Control over the Microtubule Cytoskeleton**"
L. Gao, J. C. M. Meiring, C. Heise, A. Rai, A. Muller-Deku, A. Akhmanova, J. Thorn-Seshold, O. Thorn-Seshold (B09)
Angewandte Chemie-International Edition, 2022, 61 (10), DOI: 10.1002/anie.202114614

"Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids"
S. D. Pritzl, D. B. Konrad, M. F. Ober, A. F. Richter, J. A. Frank, B. Nickel (A07), D. Trauner (B09), T. Lohmüller (A08)
Langmuir, 2022, 38 (1), pp 385-393, DOI: 10.1021/acs.langmuir.1c02745, Publication Date (Web): 20211231

"Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision**"
A. Sailer, J. C. M. Meiring, C. Heise, L. N. Pettersson, A. Akhmanova, J. Thorn-Seshold, O. Thorn-Seshold (B09)
Angewandte Chemie-International Edition, 2021, 60 (44), pp 23695-23704, DOI: 10.1002/anie.202104794

"Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif"
J. G. Felber, L. Zeisel, L. Poczka, K. Scholzen, S. Busker, M. S. Maier, U. Theisen, C. Brandstadter, K. Becker, E. S. J. Arner, J. Thorn-Seshold, O. Thorn-Seshold (B09)
Journal of the American Chemical Society, 2021, 143 (23), pp 8791-8803, DOI: 10.1021/jacs.1c03234

"A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton"
L. Gao, J. C. M. Meiring, Y. Kraus, M. Wranik, T. Weinert, S. D. Pritzl, R. Bingham, E. Ntouliou, K. I. Jansen, N. Olieric, J. Standfuss, L. C. Kapitein, T. Lohmüller (A08), J. Ahlfeld, A. Akhmanova, M. O. Steinmetz, O. Thorn-Seshold (B09)
Cell Chemical Biology, 2021, 28 (2), pp 228-+, DOI: 10.1016/j.chembiol.2020.11.007

"Photolipid Bilayer Permeability is Controlled by Transient Pore Formation"
S. D. Pritzl, P. Urban, A. Prasselsperger, D. B. Konrad, J. A. Frank, D. Trauner (B09), T. Lohmüller (A08)
Langmuir, 2020, 36 (45), pp 13509-13515, DOI: 10.1021/acs.langmuir.0c02229

"Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton"
A. Muller-Deku, J. C. M. Meiring, K. Loy, Y. Kraus, C. Heise, R. Bingham, K. I. Jansen, X. Y. Qu, F. Bartolini, L. C. Kapitein, A. Akhmanova, J. Ahlfeld, D. Trauner (B09), O. Thorn-Seshold (B09)
Nature Communications, 2020, 11 (1), p pp 12, DOI: 10.1038/s41467-020-18389-6

"Microtubules control cellular shape and coherence in amoeboid migrating cells"
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold (B09), D. Trauner (B09), H. Hacker, K. D. Fischer, E. Kiermaier, M. Sixt
Journal of Cell Biology, 2020, 219 (6), DOI: 10.1083/jcb.201907154

"Optical Manipulation of F-Actin with Photoswitchable Small Molecules"
M. Borowiak, F. Kullmer, F. Gegenfurtner, S. Peil, V. Nasufovic, S. Zahler (B08), O. Thorn-Seshold (B09), D. Trauner (B09), H. D. Arndt
Journal of the American Chemical Society, 2020, 142 (20), pp 9240-9249, DOI: 10.1021/jacs.9b12898

"A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes"
P. Urban, S. D. Pritzl, M. F. Ober, C. F. Dirscherl, C. Pernpeintner, D. B. Konrad, J. A. Frank, D. Trauner (B09), B. Nickel (A07), T. Lohmüller (A08)
Langmuir, 2020, 36 (10), pp 2629-2634, DOI: 10.1021/acs.langmuir.9b02942

"Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo"
A. Sailer, F. Ermer, Y. Kraus, R. Hammar, F. H. Lutter, J. Ahlfeld, O. Thorn-Seshold (B09)
Beilstein Journal of Organic Chemistry, 2020, 16, pp 125-134, DOI: 10.3762/bjoc.16.14

"Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors"
Y. Kraus, C. Glas, B. Melzer, L. Gao, C. Heise, M. Preusse, J. Ahlfeld, F. Bracher, O. Thorn-Seshold (B09)
European Journal of Medicinal Chemistry, 2020, 186, DOI: 10.1016/j.ejmech.2019.111865

"Hemithioindigos for Cellular Photopharmacology: Desymmetrised Molecular Switch Scaffolds Enabling Design Control over the Isomer-Dependency of Potent Antimitotic Bioactivity"
A. Sailer, F. Ermer, Y. Kraus, F. H. Lutter, C. Donau, M. Bremerich, J. Ahlfeld, O. Thorn-Seshold (B09)
Chembiochem, 2019, 20 (10), pp 1305-1314, DOI: 10.1002/cbic.201800752

"Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides"
M. Kol, B. Williams, H. Toombs-Ruane, H. G. Franquelim, S. Korneev, C. Schroeer, P. Schwille (A09), D. Trauner (B09), J. C. M. Holthuis, J. A. Frank
Elife, 2019, 8, DOI: 10.7554/eLife.43230

"Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles"
P. Urban, S. D. Pritzl, D. B. Konrad, J. A. Frank, C. Pernpeintner, C. R. Roeske, D. Trauner (B09), T. Lohmüller (A08)
Langmuir, 2018, 34 (44), pp 13368-13374, DOI: 10.1021/acs.langmuir.8b03241

"Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis"
A. Singh, T. Saha, I. Begemann, A. Ricker, H. Nusse, O. Thorn-Seshold (B09), J. Klingauf, M. Galic, M. Matis
Nature Cell Biology, 2018, 20 (10), pp 1126-+, DOI: 10.1038/s41556-018-0193-1

"Reversible optical control of F1Fo-ATP synthase using photoswitchable inhibitors"
B. Eisel, F. W. W. Hartrampf, T. Meier, D. Trauner (B09)
Febs Letters, 2018, 592 (3), pp 343-355, DOI: 10.1002/1873-3468.12958

"Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology"
T. Podewin, J. Ast, J. Broichhagen, N. H. F. Fine, D. Nasteska, P. Leippe, M. Gailer, T. Buenaventura, N. Kanda, B. J. Jones, C. M'Kadmi, J. L. Baneres, J. Marie, A. Tomas, D. Trauner (B09), A. Hoffmann-Roder, D. J. Hodson
Acs Central Science, 2018, 4 (2), pp 166-179, DOI: 10.1021/acscentsci.7b00237

"Synthesis of Photoswitchable Delta(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling"
M. V. Westphal, M. A. Schafroth, R. C. Sarott, M. A. Imhof, C. P. Bold, P. Leippe, A. Dhopeshwarkar, J. M. Grandner, V. Katritch, K. Mackie, D. Trauner (B09), E. M. Carreira, J. A. Frank
Journal of the American Chemical Society, 2017, 139 (50), pp 18206-18212, DOI: 10.1021/jacs.7b06456

"Specificity and Speed: Tethered Photopharmacology"
P. Leippe, J. K. Leman, D. Trauner (B09)
Biochemistry, 2017, 56 (39), pp 5214-5220, DOI: 10.1021/acs.biochem.7b00687

"Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles"
C. Pernpeintner, J. A. Frank, P. Urban, C. R. Roeske, S. D. Pritzl, D. Trauner (B09), T. Lohmüller (A08)
Langmuir, 2017, 33 (16), pp 4083-4089, DOI: 10.1021/acs.langmuir.7b01020

"Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors"
J. Levitz, J. Broichhagen, P. Leippe, D. Konrad, D. Trauner (B09), E. Y. Isacoff
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (17), pp E3546-E3554, DOI: 10.1073/pnas.1619652114

"Optical Control of Lipid Rafts with Photoswitchable Ceramides"
J. A. Frank, H. G. Franquelim, P. Schwille (A09), D. Trauner (B09)
Journal of the American Chemical Society, 2016, 138 (39), pp 12981-12986, DOI: 10.1021/jacs.6b07278

"Photoswitchable diacylglycerols enable optical control of protein kinase C"
J. A. Frank, D. A. Yushchenko, D. J. Hodson, N. Lipstein, J. Nagpal, G. A. Rutter, J. S. Rhee, A. Gottschalk, N. Brose, C. Schultz, D. Trauner (B09)
Nature Chemical Biology, 2016, 12 (9), pp 755-+, DOI: 10.1038/nchembio.2141

"A Roadmap to Success in Photopharmacology"
J. Broichhagen, J. A. Frank, D. Trauner (B09)
Accounts of Chemical Research, 2015, 48 (7), pp 1947-1960, DOI: 10.1021/acs.accounts.5b00129

"Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death"
M. Borowiak, W. Nahaboo, M. Reynders, K. Nekolla, P. Jalinot, J. Hasserodt, M. Rehberg (B10), M. Delattre, S. Zahler (B08), A. Vollmar, D. Trauner (B09), O. Thorn-Seshold
Cell, 2015, 162 (2), pp 403-411, DOI: 10.1016/j.cell.2015.06.049

"Photoswitchable fatty acids enable optical control of TRPV1"
J. A. Frank, M. Moroni, R. Moshourab, M. Sumser, G. R. Lewin, D. Trauner (B09)
Nature Communications, 2015, 6, DOI: 10.1038/ncomms8118

"A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function"
J. Broichhagen, J. A. Frank, N. R. Johnston, R. K. Mitchell, K. Smid, P. Marchetti, M. Bugliani, G. A. Rutter, D. Trauner (B09), D. J. Hodson
Chemical Communications, 2015, 51 (27), pp 6018-6021, DOI: 10.1039/c5cc01224d

B10

"Dexamethasone-conjugated DNA nanotubes as anti-inflammatory agents in vivo"
S. Sellner, S. Kocabey, T. Zhang, K. Nekolla, S. Hutten, F. Krombach (B10), T. Liedl (A06), M. Rehberg (B10)
Biomaterials, 2017, 134, pp 78-90, DOI: 10.1016/j.biomaterials.2017.04.031

"New View on Endothelial Cell Migration Switching Modes of Migration Based on Matrix Composition"
K. Kick, K. Nekolla, M. Rehberg (B10), A. M. Vollmar, S. Zahler (B08)
Arteriosclerosis Thrombosis and Vascular Biology, 2016, 36 (12), pp 2346-2357, DOI: 10.1161/ATVBAHA.116.307870

"Multiphoton Microscopy of Nonfluorescent Nanoparticles In Vitro and In Vivo"
S. Dietzel, S. Hermann, Y. Kugel, S. Sellner, E. Uhl, S. Hirn, F. Krombach (B10), M. Rehberg (B10)
Small, 2016, 12 (24), pp 3245-3257, DOI: 10.1002/smll.201503766

"Influence of Surface Modifications on the Spatiotemporal Microdistribution of Quantum Dots In Vivo"
K. Nekolla, K. Kick, S. Sellner, K. Mildner, S. Zahler (B08), D. Zeuschner, F. Krombach (B10), M. Rehberg (B10)
Small, 2016, 12 (19), pp 2641-2651, DOI: 10.1002/smll.201600071

"Intercellular Transport of Nanomaterials is Mediated by Membrane Nanotubes In Vivo"
M. Rehberg, K. Nekolla, S. Sellner, M. Praetner, K. Mildner, D. Zeuschner, F. Krombach (B10)
Small, 2016, 12 (14), pp 1882-1890, DOI: 10.1002/smll.201503606

"Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death"
M. Borowiak, W. Nahaboo, M. Reynders, K. Nekolla, P. Jalinot, J. Hasserodt, M. Rehberg (B10), M. Delattre, S. Zahler (B08), A. Vollmar, D. Trauner (B09), O. Thorn-Seshold
Cell, 2015, 162 (2), pp 403-411, DOI: 10.1016/j.cell.2015.06.049

"DNA nanotubes as intracellular delivery vehicles in vivo"
S. Sellner, S. Kocabey, K. Nekolla, F. Krombach (B10), T. Liedl (A06), M. Rehberg (B10)
Biomaterials, 2015, 53, pp 453-463, DOI: 10.1016/j.biomaterials.2015.02.099

"A microfluidics approach to study the accumulation of molecules at basal lamina interfaces"
F. Arends, S. Sellner, P. Seifert, U. Gerland (A03), M. Rehberg (B10), O. Lieleg (B07)
Lab on a Chip, 2015, 15 (16), pp 3326-3334, DOI: 10.1039/c5lc00561b

"Label-Free Determination of Hemodynamic Parameters in the Microcirculaton with Third Harmonic Generation Microscopy"
S. Dietzel, J. Pircher, A. K. Nekolla, M. Gull, A. W. Brandli, U. Pohl, M. Rehberg (B10)
PLoS One, 2014, 9 (6), DOI: 10.1371/journal.pone.0099615

B11

"Mesoporous Biodegradable Magnesium Phosphate-Citrate Nanocarriers Amplify Methotrexate Anticancer Activity in HeLa Cells"
L. Wehl, C. von Schirnding, M. C. Bayer, O. Zhuzhgova, H. Engelke (B11), T. Bein
Bioconjugate Chemistry, 2022, 33 (4), pp 566-575, DOI: 10.1021/acs.bioconjchem.1c00565

"Directed invasion of cancer cell spheroids inside 3D collagen matrices oriented by microfluidic flow in experiment and simulation"
F. Geiger, L. G. Schnitzler, M. S. Brugger, C. Westerhausen, H. Engelke (B11)
PLoS One, 2022, 17 (3), p pp e0264571, DOI: 10.1371/journal.pone.0264571, Publication Date (Web): 20220301

"Liquid-liquid phase separation underpins the formation of replication factories in rotaviruses"
F. Geiger, J. Acker, G. Papa, X. Y. Wang, W. E. Arter, K. L. Saar, N. A. Erkamp, R. Z. Qi, J. P. Bravo, S. Strauss, G. Krainer, O. R. Burrone, R. Jungmann (A11), T. P. J. Knowles, H. Engelke (B11), A. Borodavka
Embo Journal, 2021, 40 (21), DOI: 10.15252/embj.2021107711

"Protocol for photoactivation of YAP in cancer cell spheroids embedded in collagen gels"
B. Illes, H. Engelke (B11)
STAR Protoc, 2021, 2 (3), p pp 100657, DOI: 10.1016/j.xpro.2021.100657, Publication Date (Web): 20210707

"Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids"
B. Illes, A. Fuchs, F. Gegenfurtner, E. Ploetz, S. Zahler (B08), A. M. Vollmar, H. Engelke (B11)
iScience, 2021, 24 (3), DOI: 10.1016/j.isci.2021.102185

"Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice"
J. Wagner, D. Gossl, N. Ustyanovska, M. Y. Xiong, D. Hauser, O. Zhuzhgova, S. Hocevar, B. Taskoparan, L. Poller, S. Datz, H. Engelke (B11), Y. Daali, T. Bein (B05), C. Bourquin
ACS Nano, 2021, 15 (3), pp 4450-4466, DOI: 10.1021/acsnano.0c08384

"Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors"
C. von Schirnding, I. Giopanou, A. Hermawan, L. Wehl, G. Ntaliarda, B. Illes, S. Datz, F. Geisslinger, K. Bartel, A. K. Sommer, M. Lianou, V. Weiss, J. Feckl, A. M. Vollmar, C. Brauchle, G. T. Stathopoulos, E. Wagner (B04), A. Roidl, T. Bein (B05), H. Engelke (B11)
Chem, 2021, 7 (2), pp 480-494, DOI: 10.1016/j.chempr.2020.11.021

"Supersensitive Multifluorophore RNA-FISH for Early Virus Detection and Flow-FISH by Using Click Chemistry"
N. Raddaoui, S. Croce, F. Geiger, A. Borodavka, L. Mockl, S. Stazzoni, B. Viverge, C. Brauchle, T. Frischmuth, H. Engelke (B11), T. Carell (A05)
Chembiochem, 2020, 21 (15), pp 2214-2218, DOI: 10.1002/cbic.202000081

"Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles"
L. Haddick, W. Zhang, S. Reinhard, K. Moller, H. Engelke (B11), E. Wagner (B04), T. Bein (B05)
Pharmaceutics, 2020, 12 (6), DOI: 10.3390/pharmaceutics12060505

"Metal-Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH"
E. Ploetz, A. Zimpel, V. Cauda, D. Bauer, D. C. Lamb (B03), C. Haisch, S. Zahler (B08), A. M. Vollmar, S. Wuttke, H. Engelke (B11)
Advanced Materials, 2020, 32 (19), p pp 8, DOI: 10.1002/adma.201907267

"Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels"
F. Geiger, D. Rudiger, S. Zahler (B08), H. Engelke (B11)
PLoS One, 2019, 14 (11), DOI: 10.1371/journal.pone.0225215

"Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface"
A. Zimpel, N. Al Danaf, B. Steinborn, J. Kuhn, M. Hohn, T. Bauer, P. Hirschle, W. Schrimpf, H. Engelke (B11), E. Wagner (B04), M. Barz, D. C. Lamb (B03), U. Lachelt, S. Wuttke
ACS Nano, 2019, 13 (4), pp 3884-3895, DOI: 10.1021/acsnano.8b06287

"Highly active enzymes immobilized in large pore colloidal mesoporous silica nanoparticles"
D. Gossl, H. Singer, H. Y. Chiu, A. Schmidt, M. Lichtnecker, H. Engelke (B11), T. Bein (B05)
New Journal of Chemistry, 2019, 43 (4), pp 1671-1680, DOI: 10.1039/c8nj04585b

"Biocompatible crosslinked -cyclodextrin nanoparticles as multifunctional carriers for cellular delivery"
S. Datz, B. Illes, D. Gossl, C. V. Schirnding, H. Engelke (B11), T. Bein (B05)
Nanoscale, 2018, 10 (34), pp 16284-16292, DOI: 10.1039/c8nr02462f

"Invasiveness of Cells Leads to Changes in Their Interaction Behavior with the Glycocalyx"
E. Broda, A. A. Torrano, L. Lobbert, L. Mockl, C. Brauchle, H. Engelke (B11)
Advanced Biosystems, 2018, 2 (8), DOI: 10.1002/adbi.201800083

"Guiding 3D cell migration in deformed synthetic hydrogel microstructures"
M. Dietrich, H. Le Roy, D. B. Bruckner, H. Engelke (B11), R. Zantl, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Soft Matter, 2018, 14 (15), pp 2816-2826, DOI: 10.1039/c8sm00018b

"Clickable Multifunctional Large-Pore Mesoporous Silica Nanoparticles as Nanocarriers"
H. Y. Chiu, D. Goss, L. Haddick, H. Engelke (B11), T. Bein (B05)
Chemistry of Materials, 2018, 30 (3), pp 644-654, DOI: 10.1021/acs.chemmater.7b03472

"Nanoparticle mediated delivery and small molecule triggered activation of proteins in the nucleus"
H. Y. Chiu, J. A. Bates, J. Helma, H. Engelke (B11), H. Harz, T. Bein (B05), H. Leonhardt
Nucleus, 2018, 9 (1), pp 530-542, DOI: 10.1080/19491034.2018.1523665

"Liposome-Coated Iron Fumarate Metal-Organic Framework Nanoparticles for Combination Therapy"
B. Illes, S. Wuttke, H. Engelke (B11)
Nanomaterials, 2017, 7 (11), DOI: 10.3390/nano7110351

"Exosome-Coated Metal-Organic Framework Nanoparticles: An Efficient Drug Delivery Platform"
B. Illes, P. Hirschle, S. Baenert, V. Cauda, S. Wuttke, H. Engelke (B11)
Chemistry of Materials, 2017, 29 (19), pp 8042-8046, DOI: 10.1021/acs.chemmater.7b02358

"Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ"
N. Raddaoui, S. Stazzoni, L. Mockl, B. Viverge, F. Geiger, H. Engelke (B11), C. Brauchle, T. Carell (A05)
Chembiochem, 2017, 18 (17), pp 1716-1720, DOI: 10.1002/cbic.201700209

"Lipid bilayer-coated curcumin-based mesoporous organosilica nanoparticles for cellular delivery"
S. Datz, H. Engelke (B11), C. V. Schirnding, L. Nguyen, T. Bein (B05)
Microporous and Mesoporous Materials, 2016, 225, pp 371-377, DOI: 10.1016/j.micromeso.2015.12.006

"Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time"
H. Y. Chiu, W. Deng, H. Engelke (B11), J. Helma, H. Leonhardt, T. Bein (B05)
Scientific Reports, 2016, 6, DOI: 10.1038/srep25019

"Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers"
A. Zimpel, T. Preiss, R. Roder, H. Engelke (B11), M. Ingrisch, M. Peller, J. O. Rädler (A07&B01), E. Wagner (B04), T. Bein (B05), U. Lachelt, S. Wuttke
Chemistry of Materials, 2016, 28 (10), pp 3318-3326, DOI: 10.1021/acs.chemmater.6b00180

"Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps"
K. Moller, K. Muller, H. Engelke (B11), C. Brauchle, E. Wagner (B04), T. Bein (B05)
Nanoscale, 2016, 8 (7), pp 4007-4019, DOI: 10.1039/c5nr06246b

"Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release"
S. Datz, C. Argyo, M. Gattner, V. Weiss, K. Brunner, J. Bretzler, C. von Schirnding, A. A. Torrano, F. Spada, M. Vrabel, H. Engelke (B11), C. Brauchle, T. Carell (A05), T. Bein (B05)
Nanoscale, 2016, 8 (15), pp 8101-8110, DOI: 10.1039/c5nr08163g

B12

"Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration"
T. Zisis, D. B. Bruckner, T. Brandstatter, W. X. Siow, J. d'Alessandro, A. M. Vollmar, C. P. Broedersz (B12), S. Zahler (B08)
Biophysical Journal, 2022, 121 (1), pp 44-60, DOI: 10.1016/j.bpj.2021.12.006

"Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control"
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R. Chait, R. Hauschild, J. Lange, C. Guet, M. Sixt, S. Zahler (B08)
Acs Applied Materials & Interfaces, 2021, 13 (30), pp 35545-35560, DOI: 10.1021/acsami.1c09850

"Learning the dynamics of cell-cell interactions in confined cell migration"
D. B. Bruckner, N. Arlt, A. Fink, P. Ronceray, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (7), DOI: 10.1073/pnas.2016602118

"Inferring the Dynamics of Underdamped Stochastic Systems"
D. B. Bruckner, P. Ronceray, C. P. Broedersz (B12)
Physical Review Letters, 2020, 125 (5), DOI: 10.1103/PhysRevLett.125.058103

"Area and Geometry Dependence of Cell Migration in Asymmetric Two-State Micropatterns"
A. Fink, D. B. Bruckner, C. Schreiber, P. J. F. Rottgermann, C. P. Broedersz (B12), J. O. Rädler (A07&B01)
Biophysical Journal, 2020, 118 (3), pp 552-564, DOI: 10.1016/j.bpj.2019.11.3389

"Stochastic nonlinear dynamics of confined cell migration in two-state systems"
D. B. Bruckner, A. Fink, C. Schreiber, P. J. F. Rottgermann, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Nature Physics, 2019, 15 (6), pp 595-+, DOI: 10.1038/s41567-019-0445-4

"Fiber plucking by molecular motors yields large emergent contractility in stiff biopolymer networks"
P. Ronceray, C. P. Broedersz (B12), M. Lenz
Soft Matter, 2019, 15 (7), pp 1481-1487, DOI: 10.1039/c8sm00979a

"Stress-dependent amplification of active forces in nonlinear elastic media"
P. Ronceray, C. P. Broedersz (B12), M. Lenz
Soft Matter, 2019, 15 (2), pp 331-338, DOI: 10.1039/c8sm00949j

"Guiding 3D cell migration in deformed synthetic hydrogel microstructures"
M. Dietrich, H. Le Roy, D. B. Bruckner, H. Engelke (B11), R. Zantl, J. O. Rädler (A07&B01), C. P. Broedersz (B12)
Soft Matter, 2018, 14 (15), pp 2816-2826, DOI: 10.1039/c8sm00018b

"Cell contraction induces long-ranged stress stiffening in the extracellular matrix"
Y. L. Han, P. Ronceray, G. Q. Xu, A. Malandrino, R. D. Kamm, M. Lenz, C. P. Broedersz (B12), M. Guo
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (16), pp 4075-4080, DOI: 10.1073/pnas.1722619115

"Morphology and Motility of Cells on Soft Substrates"
A. Goychuk, D. B. Brückner, A. W. Holle, J. P. Spatz, C. P. Broedersz (B12), E. Frey (B02)
arXiv preprint, 2018, DOI: 10.48550/ARXIV.1808.00314

"Physical limits to biomechanical sensing in disordered fibre networks"
F. Beroz, L. M. Jawerth, S. Munster, D. A. Weitz, C. P. Broedersz (B12), N. S. Wingreen
Nature Communications, 2017, 8, DOI: 10.1038/ncomms16096

"Fiber networks amplify active stress"
P. Ronceray, C. P. Broedersz (B12), M. Lenz
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (11), pp 2827-2832, DOI: 10.1073/pnas.1514208113

"Multi-scale strain-stiffening of semiflexible bundle networks"
I. K. Piechocka, K. A. Jansen, C. P. Broedersz (B12), N. A. Kurniawan, F. C. MacKintosh, G. H. Koenderink
Soft Matter, 2016, 12 (7), pp 2145-2156, DOI: 10.1039/c5sm01992c